Jurassic Park
Jurassic Park takes place on a fictional island in the pacific, where a company is genetically resurrecting dinosaurs for their amusement park. Dinosaur DNA sequences are filled in with that of living ancestors. Hammond, the CEO of the company invites paleontologists and other experts to determine the safety of the park. The park is eventually sabotaged, with many dinosaurs being released, and the genetic tampering of the biology of the dinosaurs has unforeseen consequences. The dinosaurs had DNA genetically filled in with frog DNA, and they were all made female so their population does not get out of control, but the frog DNA causes them to spontaneously change gender and reproduce.
Jurassic Park was conceived and film in the a time when things like the Human Genome Project, which began in 1990, had great public attention. Genetic engineering seemed for the first time actually within real science’s reach, not just science fiction. This might be why the apparently realistic genetics of Jurassic Park was so appealing.
Same as time depicted.
While the feasibility of the genetics is debated, the ethical implications. The franchise was created in the spirit of Mary Shelley’s Frankenstein, and could perhaps be considered a modern adaptation of it. While none of the scientists were “mad” or “bad”, their morality was dubious and didn’t take into consideration what they were meddling with, and their egos often got in the way, such as Hammond’s. Lack of foresight or constraints when it comes to playing God makes for equally cataclysmic events as evil egos do.
This would be used as a modern, genetically and scientifically savvy version of Shelly's Frankenstein, as well as showing even with good intentions and a stable mind, playing god can make scientists just like evil ones.